Graduate student Linda Su-Feher’s abstract was selected for a talk at the nanosymposium “Genomic Engineering Using Enhancers or CRISPR” at the Society for Neuroscience (SfN) meeting in Chicago. She will present our work on developing a functional enhancer assay to test DNA sequences for enhancer activity in vivo in mouse brain. Meet with Linda and other members of the Nord lab at SfN.
A new Nord lab paper was published in Frontiers in Molecular Neuroscience on January 14th, 2019. Ayanna Wade (graduate student) is first author on the paper with Rinaldo Catta-Pretta (graduate student) and Justin Lim (technician) as co-authors. This work featuring comparative analysis of Chd8 RNA-seq and ChIP-seq datasets suggests conserved high confidence Chd8 genomic targets are related to transcriptomic pathology in Chd8 mutation and knockdown models. Find the paper here.
Graduate student Ayanna Wade and Postdoc Jason Lambert represented the Nord lab by presenting posters at the Cold Spring Harbor Laboratory’s annual Biology of Genomes meeting held May 8th-12th in Cold Spring Harbor, NY.
Dlx1 and Dlx2 in cortical interneuron generation. Read ‘Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis’ at Cerebral Cortex here. Congratulations to all the authors!
The Nord Lab’s work characterizing brain development in a mouse model of the autism risk gene Chd8 is published online in Nature Neuroscience on June 26th, 2017! Andrea Gompers (postdoc) and Linda Su-Feher (graduate student) are co-first authors from the lab. This work was a collaboration between the Nord Lab and the labs of Jacqueline Crawley and Jill Silverman (UC Davis MIND Institute), Jason Lerch (The Hospital for Sick Children, Toronto), and Konstantinos Zarbalis (Shriners Hospitals for Children).
This manuscript was partially produced by copious amounts of coffee and group huddles in exasperated cafes.
We are hiring for two postdocs starting October 24th for newly funded research on enhancer biology. Strong candidates will have experience with genomic and AAV technologies applied to in vitro and in vivo models. See position posting on the SfN jobs website or follow the link on the lab homepage.
New paper in Neuron on using enhancers to study brain development. Congrats to Shanni Silberberg and John Rubenstein who led the work. We contributed to the genomic analysis of brain enhancers. Read more: https://www.ncbi.nlm.nih.gov/pubmed/27710791
Nord Lab contributes to a study identifying genetic loci that impact myocardial mass. We contributed to analysis showing that common genetic variants impact heart enhancers. Read more: https://www.ncbi.nlm.nih.gov/pubmed/27659466